Авторы: Zharikov A.N., Lubyansky V.G., Gladysheva E.K., Skiba E.A., Budaeva V.V., Semenova E.N., Motin Yu.G., Zharikov A.A.
Название публикации: Prosthetic hernioplasty using bacterial nanocellulose: An experimental study
Название источника: Clinical and Experimental Surgery
Библиографическая ссылка: Zharikov A.N., Lubyansky V.G., Gladysheva E.K., Skiba E.A., Budaeva V.V., Semenova E.N., Motin Yu.G., Zharikov A.A. Prosthetic hernioplasty using bacterial nanocellulose: An experimental study // Clinical and Experimental Surgery. - 2018. - Vol.6. - Iss.2. - P.59-66.
Библиографическая ссылка2: Clin. Experiment. Surg. Petrovsky J. 2018; 6 (2): 59–66.
Ссылки: DOI: 10.24411/2308-1198-2018-12008; SCOPUS: 2-s2.0-85049035418; РИНЦ: 35079491;
Реферат: The aim is to evaluate the possibility of using bacterial cellulose as a material for a hernioplasty of prosthetic hernia of the anterior abdominal wall. Material and methods. In experimental studies on dogs, the possibility of prosthetics of a defect in the anterior abdominal wall was studied using new materials. The plates of moist (99.9%) bacterial nanocellulose (BNC), obtained by biosynthesis with the symbiotic culture of Medusomyces giseviiSa-12, were used as the prosthetic material. Biological synthesis of BNC was carried out on nutrient medium, basically consisting of enzymatic hydrolyzate of cellulose from fruit shells of oats. All tech- nological stages of obtaining BNC from fruit shells of oats are carried out according to the author’s patented method. The resulting bacterial cellulose is chemically pure cellulose, has a crystallinity of 88%, and consists of a triclinic phase Iα of 99%. Hernia of the anterior abdominal wall was modeled by performing a mid-median laparotomy. In the future, the plate of bacterial cellulose was fixed to the unclosed edges of the aponeurosis. Along with this, a comparative study of the strengthening of the aponeurosis defect, both with the BNC plate, and with a piece of polypropylene mesh “Ulrapro” (Ethikon) was carried out. On 14th and 60th days a material was taken with a visual assessment of its location in the tissues of the anterior abdominal wall and subsequent histological examination. The microscopy of the obtained BNC samples was additionally performed. Results. A good fixation of the BNC material in the tissues of the anterior abdominal wall was established with the formation of a capsule of soft tissues on the 14th day around it, the subsequent degradation of the BNC on the 60th day of the postoperative period was shown, with the development of active repair processes in the area of material placement and replacement by its stable newly formed connective tissue elements (fibroblasts, fibrin), less pronounced in comparison with the fixation of the polypropylene mesh, no purulent complications were found during the entire postoperative period. Conclusion. The obtained results show the possibility of using bacterial nanocellulose for prosthetic hernioplasty.
Ключевые слова: hernia of the anterior abdominal wall, prosthetic hernioplasty, bacterial nanocellulose
Год опуликования: 2018
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